Letter Re: Understanding Human Immune System Response to Infection

Sunday, Oct 30, 2005

Hello! I just finished reading Patriots   for a third time - INCREDIBLE book. I'm also a good friend of "Dr. Buckaroo Banzai." I have a master's degree in immunology and teach in a nursing program at a local college. My comments are aimed at the general education of the readership of your blog. The immune system operates largely on the function of T-helper cells. There are two main T-helper varieties. One variety (T-h1) deals with intracellular pathogens (viruses, few bacteria) and the other (T-h2) deals with extra-cellular pathogens (majority of bacteria, protozoa, fungi).  What separates these two groups are the cytokines (chemicals which modulate immune response) that are released. T-h1 cytokines promote immunity to intracellular pathogens AND SUPRESS the function of T-h2 cells. What this means is that the body's response to a viral infection WILL leave the patient more susceptible to a bacterial infection. The opposite is true as well - bacterial infections leave the body less prepared to deal with viral infections. Just thought you'd want some of the background here! Keep up the good work, keep your powder dry, and God bless! - Dr. Rocky J. Squirrel


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